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Pharmacy-International-Direct >> Diabetes >> Actos- Buy Actos

Actos
Generic Actos Actos (pioglitazone) is an oral diabetes medicine that helps control blood sugar levels. Actos is for people with type 2 (non-insulin-dependent) diabetes. Pioglitazone is sometimes used in combination with insulin or other medications, but it is not for treating type 1 diabetes.
Product Name mg Quantity Retail Price  Price Price Per Pill Buy
Actos 30 30 $ 362.00 $ 115.00 $ 3.83  
Actos 30 60 $ 450.00 $ 150.00 $ 2.50  
Actos 30 90 $ 562.00 $ 195.00 $ 2.17  
 

Generic Actos


Generic Actos is a drug that reduces the amount of glucose (sugar) in the blood. It is in a class of anti-diabetic drugs called "thiazolidinediones" that are used in the treatment of type II diabetes. The other member in this class is rosiglitazone (Avandia). (Another member of this class, troglitazone or Rezulin, was removed from the market because of liver toxicity.) Patients with type II diabetes cannot make enough insulin, and the cells of their body do not respond normally to the reduced amounts of insulin that are present. (Insulin is the hormone produced by the pancreas that stimulates cells to remove glucose from the blood.) Pioglitazone often is referred to as an "insulin sensitizer" because it attaches to the insulin receptors on cells throughout the body and causes the cells to become more sensitive (more responsive) to insulin. As a result, more glucose is removed from the blood. At least some insulin must be produced by the pancreas in order for pioglitazone to work. Pioglitazone also lowers the level of glucose in the blood by reducing the production and secretion of glucose into the blood by the liver. In addition, pioglitazone may alter the blood concentrations of lipids (fats) in the blood. Specifically, it decreases triglycerides and increases the "good" (HDL) cholesterol. Pioglitazone received FDA approval on July 16, 1999.

 

Preparations


Tablets 30mg.

 

Storage


Generic Actos should be kept at room temperature, 15-30°C (59-86°F).

 

Prescribed For


Generic Actos is used for the treatment of type II diabetes along with a healthy diabetic diet, regular exercise, weight control, smoking reduction, and careful monitoring of blood glucose. Pioglitazone may be used alone or in combination with metformin , a drug in a different class of anti-diabetic drugs, that also lowers blood glucose. Since it requires naturally-secreted insulin to be effective, pioglitazone is not recommended in type I diabetes where the amount of insulin is very low or absent. Nevertheless, pioglitazone is approved for treating type II diabetes in combination with insulin as well as another class of anti-diabetic drugs, the sulfonylureas.

 

Dosing


Generic Actos is prescribed once daily in doses ranging from 15 to 45 mg. Pioglitazone may be taken any time of the day, with or without meals. If a dose is missed on one day, two doses should not be taken the next day to make up for the missed dose.

 

Drug Interactions


To date, no formal studies to evaluate drug interactions of pioglitazone with other drugs have been conducted. However, since another thiazolidinedione that is similar to pioglitazone may reduce the effectiveness of oral contraceptives (potentially leading to pregnancy), caution should be used when using pioglitazone with an oral contraceptive. Clinical studies using pioglitazone 15-45mg did not reveal changes in blood levels for the following drugs: glipizide , digoxin , warfarin or metformin. In addition, the clotting of blood did not appear to be changed enough by pioglitazone to require alterations in the doses of the blood thinner, warfarin.

 

Pregnancy


There are no adequate studies of pioglitazone in pregnant women. Pioglitazone may be used in pregnancy if the physician feels the potential risks are justified.

 

Nursing Mothers


It is unknown if pioglitazone is secreted in breast milk. Therefore, the safety to a nursing infant when the mother is taking pioglitazone is unknown.

 

Side Effects


Headache; muscle aches; sore throat; weight gain.

 

 
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