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Pharmacy-International-Direct >> Diabetes >> Avandia- Buy Avandia

Avandia
Generic Avandia Avandia (rosiglitazone) is an oral diabetes medicine that helps control blood sugar levels. Avandia is for people with type 2 (non-insulin-dependent) diabetes. It is sometimes used in combination with insulin or other medications.
Product Name mg Quantity Retail Price  Price Price Per Pill Buy
Avandia 8 30 $ 432.00 $ 143.00 $ 4.77  
Avandia 8 60 $ 540.00 $ 186.00 $ 3.10  
Avandia 8 90 $ 602.00 $ 243.00 $ 2.70  
 

Generic Avandia


Generic Avandia is a drug that reduces the amount of glucose (sugar) in the blood. It is in a class of anti-diabetic drugs called "thiazolidinediones" that are used in the treatment of type II diabetes. The other member in this class is pioglitazone (Actos). (Another member of this class, troglitazone or Rezulin, was removed from the market because of liver toxicity.) Patients with type II diabetes cannot make enough insulin, and the cells of their body do not respond normally to the reduced amounts of insulin that are present. (Insulin is the hormone produced by the pancreas that stimulates cells to remove glucose from the blood.) Rosiglitazone often is referred to as an "insulin sensitizer" because it attaches to the insulin receptors on cells throughout the body and causes the cells to become more sensitive (more responsive) to insulin. As a result, more glucose is removed from the blood. At least some insulin must be produced by the pancreas in order for rosiglitazone to function. Rosiglitazone was approved by the FDA on May 28, 1999.

 

Preparations


Film-coated tablets: 8 mg.

 

Storage


Generic Avandia tablets should be kept at room temperature, 15-30°C (59-86°F).

 

Prescribed For


Generic Avandia is used for the treatment of type II diabetes along with a healthy diabetic diet, regular exercise, weight control, smoking reduction, and careful monitoring of blood glucose. Rosiglitazone may be used alone or in combination with metformin , another type of anti-diabetic drug that also lowers blood glucose, sulfonylureas, another class of anti-diabetic drug, or insulin in type II diabetes. Since it requires naturally-secreted insulin to be effective, rosiglitazone is not recommended in type I diabetes where the amount of insulin is very low or absent.

 

Dosing


Generic Avandia may be taken once or twice daily, with or without meals. Daily doses range from 4 to 8 mg either with or without metformin. Studies do not demonstrate additional effects when more than 8mg per day are taken.

 

Drug Interaction


Drug interactions seen with the other two anti-diabetic thiazolidinedione drugs have not been seen with rosiglitazone because it has a different method of elimination from the body. Studies using rosiglitazone, 4-8 mg per day, did not cause changes in blood levels of the commonly-used drugs, digoxin and warfarin . Alcohol did not interact with rosiglitazone (reduce the level of blood sugar further) when the alcohol consumption was limited to a single episode of moderate consumption.

 

Pregnancy


There are no adequate studies of rosiglitazone in pregnant women. Rosiglitazone may be used in pregnancy if the physician judges the potential risks to be outweighed by the benefits.

 

Nursing Mothers


It is unknown if rosiglitazone is secreted in breast milk. Therefore, the safety of rosiglitazone to nursing infants also is unknown.

 

Side Effects


The most common side effects seen with rosiglitazone alone or in combination with metformin are upper respiratory tract infection, headache, back pain, hyperglycemia, fatigue, sinusitis , diarrhea , and hypoglycemia .

 

 
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