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Pharmacy-International-Direct >> Sexual Health >> Cialis Tadalafil- Buy Generic Cialis

Generic Cialis
Generic Cialis is an oral drug, used for treating male impotence. This medication relaxes muscles in the penis and increases blood flow in it, thereby helping men to achieve and maintain an erection. It is the only drug which is not only fast acting but is also know to be effective for as long as 36 hours, thus enabling you to choose the moment that is just right for you as well as your partner.
Product Name mg Quantity Retail Price  Price Price Per Pill Buy
Generic Cialis 20 10 $ 172.00 $ 39.00 $ 3.90  
Generic Cialis 20 30 $ 322.00 $ 89.00 $ 2.97  
Generic Cialis 20 60 $ 390.00 $ 115.00 $ 1.92  
Generic Cialis 20 90 $ 495.00 $ 159.00 $ 1.77  
Generic Cialis 20 120 $ 622.00 $ 199.00 $ 1.66  
Generic Cialis 20 150 $ 670.00 $ 229.00 $ 1.53  
Generic Cialis 20 300 $ 1,125.00 $ 359.00 $ 1.20  
Generic Cialis 20 600 $ 1,765.00 $ 585.00 $ 0.98  
 

Generic Cialis


Tadalafil is an oral drug that is used to treat impotence (the inability to attain or maintain a penile erection.). It is a phosphodiesterase inhibitor that is similar to sildenafil (Viagra) and vardenafil (Levitra). Penile erection is caused by the engorgement of the penis with blood. This engorgement occurs when the blood vessels delivering blood to the penis increase in size and increase the delivery of blood to the penis. At the same time, the blood vessels carrying blood away from the penis decrease in size and decrease the removal of blood from the penis. Sexual stimulation that leads to the engorgement and erection causes the production and release of nitric oxide in the penis. Nitric oxide then activates the enzyme, guanylate cyclase to produce cyclic guanosine monophosphate (cGMP). The cGMP is primarily responsible for increasing and decreasing the size of the blood vessels carrying blood to and from the penis, respectively. Tadalafil prevents an enzyme called phosphodiesterase-5 from destroying cGMP so that cGMP persists longer. The longer cGMP persists, the more prolonged the engorgement of the penis. Tadalafil was approved by the FDA in November, 2003.

 

Preparations


Tablets 20 mg.

 

Storage


Store at room temperature between 15-30°C (59-86°F).

 

Prescribed for


Generic Cialis is used for the treatment of impotence.

 

Dosing


For most individuals, the recommended starting dose of tadalafil is 10 mg per day taken before sexual activity. Depending on the adequacy of the response or side effects, the dose may be increased to 20 mg or decreased to 5 mg a day. The effect of tadalafil may last up to 36 hours. Individuals who are taking medications that increase the blood levels of tadalafil should not exceed 10 mg in 72 hours (See drug interactions.)

 

Drug Interactions


The breakdown and elimination of tadalafil from the body may be decreased by erythromycin , ketoconazole (Nizoral), itraconazole (Sporanox), indinavir (Crixivan) and ritonavir (Norvir). Therefore, these drugs may increase the concentration of tadalafil in the blood. If these drugs are being used at the same time as tadalafil, the dose of tadalafil should be reduced in order to avoid side effects from high levels of tadalafil. Tadalafil increases the heart rate and also exaggerates the blood pressure lowering effects of nitrates (e.g., nitroglycerin ). In patients who take nitrates for chest pain ( angina ), tadalaafil could cause chest pain by increasing heart rate and lowering blood pressure. Therefore, patients with angina should not use tadalafil. Tadalafil also exaggerates the blood pressure lowering effects of some alpha-blocking drugs e.g., terazosin (Hytrin). Individuals who take these alpha-blockers should not use tadalafil.

 

Pregnancy


Tadalafil is not approved for use in pregnant women.

 

Side Effects


The most common side effects of tadalafil are facial flushing (reddening), headaches, stomach upset, diarrhea , flu-like symptoms and nausea. Tadalafil also may cause chest pain, low blood pressure , blurred vision and changes in color vision, abnormal ejaculation and priapism (prolonged and painful erection).

 

 
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