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Pharmacy-International-Direct >> Heart Failure >> Plavix- Buy Plavix

Plavix
Generic Plavix Plavix (clopidogrel) keeps the platelets in your blood from coagulating (clotting) to prevent unwanted blood clots that can occur with certain heart or blood vessel conditions. Plavix is used to prevent blood clots after a recent heart attack or stroke, and in people with certain disorders of the heart
Product Name mg Quantity Retail Price  Price Price Per Pill Buy
Plavix 75 30 $ 400.00 $ 130.00 $ 4.33  
Plavix 75 60 $ 498.00 $ 169.00 $ 2.82  
Plavix 75 90 $ 628.00 $ 221.00 $ 2.46  
 

Generic Plavix


Generic Plavix is an anti-platelet drug, that is, a drug that inhibits the ability of platelets to clump together as part of a blood clot. It is similar to ticlopidine (Ticlid) in chemical structure and in the way it works. Unlike ticlopidine, clopidogrel does not cause serious reductions of white cells in the blood and, therefore, routine blood testing to determine if the white blood cell count is low is not necessary during treatment. The risk of heart attacks and strokes (which usually are caused by blood clots) is increased in patients with a recent history of stroke or heart attack and patients with peripheral vascular disease . (Peripheral vascular disease is the same as atherosclerotic arterial disease or "hardening" of the arteries in which the arteries become narrowed. It frequently occurs in the legs and often causes claudication or pain in the legs upon walking). Clopidogrel is used to reduce the risk of heart attacks and strokes in these patients. Clopidogrel was approved by the FDA in 1997.

 

Preparation


Tablets 75mg.

 

Storage


Tablets should be stored at room temperature, 15-30°C (59-86°F).

 

Prescribed For


Generic Plavix is used to prevent strokes and heart attacks in persons who are at high risk. In one large study, clopidogrel was more effective than aspirin in reducing heart attacks. The frequency of side effects of clopidogrel was similar to aspirin; however, stomach and intestinal bleeding probably occurs less often with clopidogrel than with aspirin.

 

Dosing


Generic Plavix usually is taken once daily. It can be taken with or without food.

 

Drug Interaction


The combination of Generic Plavix with nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Motrin; Advil; Nuprin), naproxen (Naprosyn, Aleve), diclofenac (Voltaren), etodolac (Lodine), nabumetone (Relafen), fenoprofen (Nalfon), flurbiprofen (Ansaid), indomethacin (Indocin), ketoprofen (Orudis; Oruvail), oxaprozin (), piroxicam (Feldene), sulindac (Clinoril), tolmetin (Tolectin), and mefenamic acid (Ponstel) may increase the risk of stomach and intestinal bleeding. At high concentrations in the blood, clopidogrel inhibits the activity of the enzyme which metabolizes (eliminates) warfarin (Coumadin), a "blood thinner". This could lead to an increase in levels of warfarin and increase the risk of bleeding due to over-thinning of the blood. To date there have been no reports of an important interaction in humans between warfarin and clopidogrel. Nonetheless, because warfarin increases the risk of bleeding, blood tests to measure the degree to which the blood is anti-coagulated or thinned (prothrombin time; INR) may be ordered to assess the degree of blood-thinning when warfarin and clopidogrel are used together. The same enzyme also is responsible for the metabolism of phenytoin (Dilantin), tamoxifen (Nolvadex), tolbutamide (Orinase), torsemide (Demadex), and fluvastatin (Lescol). Although important interactions between clopidogrel and these drugs are unlikely, interactions should be looked for carefully.

 

Pregnancy


There are no adequate studies of Generic Plavix in pregnant women. Therefore, it can be used in pregnancy if the physician determines that it is needed.

 

Nursing Mothers


Studies in rats have shown that Generic Plavix appears in breast milk; however, it is not known whether it also appears in human breast milk. Because of a potential for side effects in the nursing infant, the physician must weigh the potential benefits and possible risks before prescribing clopidogrel in nursing mothers.

 

Side Effects


The tolerability of Generic Plavix is similar to that of aspirin. Diarrhea , rash, or itching occurs in approximately 1 in 20 persons taking Generic Plavix.

 

 
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