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Pharmacy-International-Direct >> Respiratory Disorder >> Singulair- Buy Singulair

Singulair
Generic Sigulair Singulair Editors Pick Singulair is a leukotriene (loo-koe-TRY-een) inhibitor. Leukotrienes are chemicals your body releases when you breathe in an allergen (such as pollen). These chemicals cause swelling in your lungs and tightening of the muscles around your airways, which can result in asthma symptoms
Product Name mg Quantity Retail Price  Price Price Per Pill Buy
Singulair 10 30 $ 430.00 $ 142.00 $ 4.73  
Singulair 10 60 $ 538.00 $ 185.00 $ 3.08  
Singulair 10 90 $ 678.00 $ 241.00 $ 2.68  
 

Generic Singulair


Generic Singulair is an oral leukotriene receptor antagonist for the treatment of asthma and seasonal allergic rhinitis (hay fever). Leukotrienes are a group of naturally occurring chemicals in the body that promote inflammation in asthma and seasonal allergic rhinitis and in other diseases in which inflammation is important (such as allergy ). They are formed by cells, released, and then bound to other cells, and it is the binding to these other cells that stimulates the cells to promote inflammation. Montelukast works in a manner similar to zafirlukast (Accolate), blocking the binding of some leukotrienes. Unlike zafirlukast, montelukast does not inhibit CYP2C9 or CYP3A4, two enzymes in the liver that are important in breaking down and eliminating many drugs. Therefore, unlike zafirlukast, montelukast is not expected to affect the elimination of other drugs. The safety and effectiveness of montelukast has been demonstrated in children as young as 6 years of age. It was approved by the FDA in 1998.

 

Preparations


Tablets: 10mg. Chewable tablets: 5mg.

 

Storage


Tablets should be stored at room temperature, 15-30°C (59-86°F).

 

Prescribed for


Generic Singulair is used for the treatment of asthma and seasonal allergic rhinitis. Montelukast begins working after 3 to 14 days of therapy. Therefore, it should not be used for the treatment of an acute asthmatic attack.

 

Dosing


The recommended dose of montelukast is 4, 5, or 10 mg daily. The 4mg and 5mg tablets are used in children. Montelukast should be taken in the evening with or without food.

 

Drug Interaction


Phenobarbital increases the blood concentration of montelukast by about 40%. Rifampin may have the same effect. Therefore, the dose of montelukast may need to be reduced when given concurrently with these drugs.

 

Pregnancy


Generic Singulair crosses the placenta into the fetus following oral administration to animals, but there have been no adequate studies in pregnant women to determine the effects on the fetus. Physicians may prescribe zafirlukast during pregnancy if it is felt that its benefits outweigh the potential but unknown risks to the fetus.

 

Nursing Mothers


Studies in animals have shown that montelukast is excreted in milk; however, it is not known if montelukast is secreted into breast milk in humans.

 

Side Effects


The most common side effects with montelukast are headache, dizziness , abdominal pain , sore throat , and rhinitis (inflammation of the inner lining of the nose). These side effects occur in 1 in 50 to 1 in 7 persons who take montelukast.

 

 
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